Hundreds of Bahrainis took to the streets in different villages across Bahrain on April 29, 2022, marking the Al-Quds International Day, which falls on the last Friday of the Month of Ramadan.

Ayatollah Sheikh Isa Qassim issued a statement concerning the ongoing normalization process, saying that "normalization with the Israeli enemy works towards destroying the nation's interests, pride and unity, but the Islamic mentality of the nation and its conscience are the most targeted."

Ayatollah Sheikh Isa Qassim called on the authorities to reverse the decision to imprison citizen Fadeela Abdulrasoul.

Ayatollah Sheikh Isa Qassim, spiritual leader of the Shiite sect in Bahrain, condemned the visit of the Israeli Prime Minister to Bahrain, stressing that all the people of Bahrain reject this visit.

Ayatollah Sheikh Isa Qassim issued (September 18, 2021) a statement calling on the opposition to unify their stance, in the face of government projects that seek to pass "weak formal reforms" and eliminate key demands.

Ayatollah Sheikh Isa Qassim dubbed the war on Yemen "dirty", calling for taking action to support the people of Yemen.

Ayatollah Sheikh Isa Qassim condemned "the horrific massacre that took place last Friday (October 8, 2021) targeting the faithful worshippers at a mosque in Kunduz, Afghanistan, during Friday prayers."

Ayatollah Sheikh Isa Qassim described the normalization of Bahrain's ruling regime with the Zionist entity as treason and malice.

Ayatollah Sheikh Isa Qassim thanked Haq Movement leader, Mr. Hassan Mushaima, for his honorable stance. Mushaima rejected his conditional release, describing it as humiliating.

Ayatollah Sheikh Isa Qassim said the measures imposed by the Bahraini authorities on the commemoration of Ashura are "a mere political, not sectarian, war"

Ayatollah Sheikh Isa Ahmed Qassim issued a statement on the commemoration of Ashura and precautionary measures, in which he recommended that commemoration activities be carried out according to the same preventive measures imposed on other gatherings where caution should be exercised, i.e. gatherings tolerated by the state.

Bahrain's Shiite spiritual leader Ayatollah Sheikh Isa Qassim expressed his thanks and appreciation for the Bahraini people's stance, who launched a media campaign against welcoming any commercial or tourist delegations from the Israeli occupation.

Ayatollah Sheikh Isa Qassim held the prison officers and senior officials responsible for anything that could happen to Sheikh Isa Qassim.

Ayatollah Sheikh Isa Qassim stressed that it is not religiously permissible to hold any gathering that would increase spread of the epidemic, fill hospitals with patients and claim more lives.

Ayatollah Sheikh Isa Qassim thanked the Palestinian heroes who fought the Israeli enemy to defend the nation's religion, sanctities and dignity.

Ayatollah Sheikh Isa Qassim said in a statement on Thursday (May 20, 2021) "Making Bahrain a quarantine for transients to other Gulf States and who are suspected of contacting the Coronavirus is a dangerous step which the government can't deny."

Ayatollah Sheikh Isa Qassim said that is shame to leave the Al-Aqsa and Al-Quds to the Israeli criminal desire to do whatever it wants with them.

Ayatollah Sheikh Isa Qassim said, on his Twitter page, that "the release of prisoners of political opinion in Bahrain, and the fulfillment of just human rights and political demands for security and peace, is a pride for the nation, and the contrary is the disaster of disasters."

Ayatollah Sheikh Isa Qassim called for the release of prisoners and addressed the government of Bahrain saying "Choose between releasing prisoners and keeping them to die in prisons."

"The European Parliament's testimony by a majority close to a consensus on human rights violation committed by the Bahraini government is one of the world's testimonies on this reality of the matter, which leaves no excuse for the government to evade its responsibility in correcting the situation," Sheikh Isa Qassim tweeted.